Southwest Tuna Macaroni and Cheese Casserole

Southwest Tuna Macaroni And Cheese Casserole Recipe

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Cindi Bauer


This is one of my "favorite" tuna casserole recipes! It was Stacky5 at who originally posted the recipe, but I did modify the recipe somewhat. I substituted one can of soup for another, plus I added a bit more of the macaroni. I really liked this dish reheated the next day in the microwave, as it was still nice and creamy!


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4 - 5


  • 2-1/2 cups
    uncooked macaroni (*see note)
  • 1 can
    (10-3/4 oz.) campbell's fiesta nacho cheese soup
  • 1 soup can
    filled with milk (l used 2% milk)
  • 1/2 cup
    mayonnaise (do not use salad dressing)
  • 1 cup
    shredded sharp cheddar cheese
  • 1/4 tsp.
    pepper (*or use mccormick's hot shot! seasoning)
  • 2 (5 oz.)
    cans solid white albacore tuna in water, drained well
  • 3 Tbsp
    italian-style bread crumbs
  • 2 Tbsp
    butter, melted
  • ·
    (*note: mccormick hot shot! seasoning, is a blend of black pepper and red pepper. )

How to Make Southwest Tuna Macaroni and Cheese Casserole


  1. Grease the inside of one 2-1/2 quart casserole baking dish; set dish aside.
  2. Cook macaroni according to package directions to "al dente" (9 to 11 minutes). Once cooked, drain and rinse with cold water, then drain again.
  3. While the macaroni is cooking, in a large bowl combine together, the soup, milk, and mayonnaise. Then stir in the shredded cheese, pepper, and tuna. (If desired, sprinkle in a bit of salt.)
  4. Stir in the cooked macaroni, then pour the mixture in the casserole baking dish.
  5. Sprinkle the bread crumbs evenly on top, then pour the melted butter over the bread crumbs.
  6. Place casserole (uncovered) in a 350 degree oven, and bake for 30-35 minutes. (I baked mine for 35 minutes.)
  7. Once heated through, remove from the oven and serve immediately.
  8. *Note: Whenever I make this casserole, I always use Rotini pasta, and use 3 cups, which I cook anywhere from 10-11 minutes. Also, if I don't have a can of Fiesta Nacho Cheese Soup on hand, but have a can of cheddar cheese soup, I'll use that, and I'll only use a half soup can of milk, plus a half soup can of mild salsa. I'll also substitute shredded Mexican cheese for the cheddar.

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