In a tall glass, combine powdered creamer and sweetener with 2 tbsp. very hot water; stir to dissolve. Add orange drink/juice and mix well.
Transfer contents of the glass to a blender. Add all remaining ingredients and blend at high speed until thoroughly mixed. If needed, remove blender from the base, stir mixture, and blend again.
Pour into the glass, stick a straw in it, and slurp away!