Comforting Homemade Meatloaf

"A simple meatloaf recipe is a tried-and-true standby for so many family dinners. If you don't have all the ingredients, here are some swaps!..."

INGREDIENTS
2 pounds ground beef
1 cup bread crumbs
1 onion, chopped
3 cloves garlic, minced
1 cup ketchup
1/3 cup milk
1 tablespoon Italian seasonings
1 teaspoon salt
1 cup ketchup
2 teaspoons white vinegar
3 tablespoons brown sugar (molasses or dark Karo)
1 teaspoon garlic powder
1 teaspoon onion powder
Pinch salt
Pinch black pepper
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