Fill pot with lightly salted water and bring to a boil. Stir in the macaroni and return water to a boil. Cook and stir occasionally for 8 minutes. Drain.
Melt butter in a large pot over medium heat. Add flour and whisk continually for 1 to 2 minutes to make a roux. Whisk in 2 C of the milk into the roux until smooth and add remaining milk. Raise the heat to medium high and continue cooking and stirring until thickened, but not boiling. Stir in all the shredded cheeses and 1 C of the parmesan cheese into the mixture. Once the cheeses have melted completely, fold in drained macaroni into the mixture to coat. Pour into a 9x13 inch baking pan.
Stir 1/2 C parmesan cheese, panko crumbs, and cayenne together in small bowl. Sprinkle mixture over macaroni. Drizzle olive oil over the breadcrumbs. Bake in preheated oven until golden bubbly for about 30 minutes. Allow to rest 10 minutes before serving.