In a medium bowl add the bread crumbs, italian seasoning (more or less, depending on your preference) and milk. Let stand until the bread crumbs are moist, about 5 minutes.
Add ground beef to bread crumb mixture. Mix until all ingredients are combined. Form into 1 large or two individual loaves. Sprinkle top of meatloaf with bread crumbs and 1 or 2 pats of butter cut into cubes(depending on the size of the loaf that you make:this step is optional)
Preheat oven to 350. Cook meatloaf at 350 for 15 minutes, then lower heat to 325 and continue baking for another 35-40 minutes or until meat juices run clear.