Preheat oven to 225 degrees. Spray large skillet with Pam. Sprinkle liberal amount of salt/pepper on roast with rub into all sides of roast. Moderately dust with onion/garlic powder and rub into all sides of roast. On medium high heat, sear the roast on all sides.
In a small roasting pan, pour Pepsi/Worctershire Sauce and mix together.
Put seared roast in roasting pan and spread the Golden Mushroom soup over the top (do not dillute). Place lid on roasting pan.
Bake @225 degrees for 5 hours. Your home will smell wonderful all day while this slow cooking.
This is the most tender and flavorful roast you will ever eat. The liquids/drippings from this roast makes a wonderful gravy to pour over homemade egg noodles!!